The Ever-Imminent Collapse of Evolution

Posted 8 July 2004 by

↗ The current version of this post is on the live site: https://pandasthumb.org/archives/2004/07/the-everimminen.html

Touchstone magazine this month has an issue devoted to antievolution, running under the title, “Darwin’s Last Stand?” In a question and answer section, there is a question that William A. Dembski provides an answer for:

Touchstone: Where is the ID movement going in the next ten years?  What new issues will it be exploring, and what new challenges will it be offering Darwinism?

Dembski: In the next five years, molecular Darwinism — the idea that Darwinian processes can produce complex molecular structures at the subcellular level — will be dead.  When that happens, evolutionary biology will experience a crisis of confidence because evolutionary biology hinges on the evolution of the right molecules.  I therefore foresee a Taliban-style collapse of Darwinism in the next ten years. Intelligent design will of course profit greatly from this. For ID to win the day, however, will require talented new researchers able to move this research program forward, showing how intelligent design provides better insights into biological systems than the dying Darwinian paradigm.

(Anonymous (Touchstone Magazine), (2004).  “The Measure of Design: A conversation about the past, present & future of Darwinism and Design.”  Touchstone, 17(6), pp. 60-65.)

The structure of the answer is quite interesting. Asked about the future of intelligent design, Dembski immediately responds with speculations about Darwinism.

The fact of the matter is that “intelligent design” has not, to date, offered any new challenges to any part of evolutionary biology. Every single argument made by ID advocates had its origins elsewhere, either in the biological literature or in antievolutionary sources. According to Dembski, designers are innovators, but thus far ID advocates have tallied up a big goose egg on innovative critiques of evolutionary biology.

Does ID need talented new researchers? Given the billing that the ID advocates make for themselves as “top scientists” and favorable comparisons of current ID advocates to past scientists such as Newton, Pasteur, and Darwin, it seems that the current crop of ID advocates should have found the wherewithal to “move this research program forward”. (“Create an ID research program” would be more accurate.) That these self-proclaimed wonders of science have thus far produced nothing of scientific merit corresponding to even a scientific theory of intelligent design says to me that ID is a field that talented new researchers would be well advised to assiduously avoid.

Dembski’s invocation of “the dying Darwinian paradigm” is amusing. Evolutionary biology is a dynamic field of research, with theoretical and empirical work going on in hundreds of institutions around the world. The scientific literature shows no tapering-off of reports of research into evolutionary phenomena. If there are death-like references to be made, they should be directed to “intelligent design”, where they have the advantage of accurately describing the topic: still-born, barren, moribund, putrescent. It’s simply the result of ID advocates trying, unsuccessfully, to revive the exhumed arguments of William Paley. The Paleyist corpus of arguments are ready for re-interment.

The claim that evolution will soon collapse is not a new one. In fact, it predates Darwin’s Origin of Species. This point is made clear by Glenn Morton’s More and More essay. Dembski’s claim is simply the most recent “prediction” of the imminent collapse of evolutionary biology.

One has to wonder about the “Taliban-style collapse” Dembski uses as an invidious comparison. Evolutionary biologists haven’t engaged in the egregious human rights violations that characterized the Taliban’s hegemony. The Taliban did not collapse because of consideration of empirical evidence. The Taliban “collapsed” because a massive military operation removed them from power. So, do ID advocates look to a day not far off when, faced with their persistent inability to muster either arguments or evidence that displace evolutionary biology, they will simply take up arms against evolutionary biologists? One hopes that Dembski’s unfortunate rhetoric is simply that, and not a sign of an imminent shift in ID tactics from shady political action to physical terrorism.

74 Comments

Bob Maurus · 8 July 2004

At what point did ID become - or was it always - the quintessential example of the blind leading the blind? And in this case, was it the self-blinded leading the willfully blind? To give them their due though, it did show some brilliant word-smithing abilities - they've managed to keep an empty balloon afloat in the public eye for quite a while.

charlie wagner · 8 July 2004

Wesley wrote:

Evolutionary biology is a dynamic field of research, with theoretical and empirical work going on in hundreds of institutions around the world. The scientific literature shows no tapering-off of reports of research into evolutionary phenomena.

And all of these reports support the notion that random processes and accidental mutations are incapable of generating complex, highly organized structures, processes and adaptations in which multiple processes and multiple structures support multiple functions and are integrated into the system in such a way that the structures and processes not only support their own functions, they also support the functions of other structures and processes and the overall function of the system. Can you cite any particular reference from the literature that supports the notion that random processes have such power? After all, that is the crux of the matter. Dembski is arguing (and so am I) that intelligent input is required for evolution to proceed. You, apparently are arguing that it is not required, that it can be explained by random, accidental processes. Is there anything in the literature that is supportive of your position?

Les Lane · 8 July 2004

I've just updated my ID literature search. Not surprisingly, there's still little about ID in the science literature and it's mostly negative. For a detailed list of ID references (with links).

Les Lane · 8 July 2004

I've just updated my ID literature search. Not surprisingly, there's still little about ID in the science literature and it's mostly negative. For a detailed list of ID references (with links).

Les Lane · 8 July 2004

Let's try again - I keep hitting the post button instead of preview. I've just updated my ID literature search. Not surprisingly, there's still little about ID in the science literature and it's mostly negative. For a detailed list of ID references (with links).

Wesley R. Elsberry · 8 July 2004

And all of these reports support the notion that random processes and accidental mutations are incapable of generating complex, highly organized structures, processes and adaptations in which multiple processes and multiple structures support multiple functions and are integrated into the system in such a way that the structures and processes not only support their own functions, they also support the functions of other structures and processes and the overall function of the system. Can you cite any particular reference from the literature that supports the notion that random processes have such power? After all, that is the crux of the matter. Dembski is arguing (and so am I) that intelligent input is required for evolution to proceed. You, apparently are arguing that it is not required, that it can be explained by random, accidental processes. Is there anything in the literature that is supportive of your position?

— charlie wagner
The published reports do not show incapability of evolutionary processes to account for the history and diversity of biological systems. Charlie is free to provide citations to the contrary, if he can... Biologists don't claim that evolutionary biology knows all the answers now. ID is advanced via an insistence that our current state of knowledge must have all the answers or we must turn to a conjecture of ID that has no supporting evidence whatsoever. I am arguing that intelligent design has failed to make a case for itself. Neither Dembski nor anyone else has put forward a positive empirical test of the notion that "intelligent input is required for evolution to proceed". All that ID advocates have shown themselves capable of is taking potshots at evolutionary biology. And they don't even come up with their own novel potshots; they have to borrow all their ammo from others.

Les Lane · 8 July 2004

Charlie's conclusions are reasonable if one uses only propositional logic and considers only the macroscopic. Unfortunately, the microsopic level (DNA sequence) suggests entirely random processes. It seems to require more than average intelligence and insight to get beyond propositional logic and to see randomness.

Russell · 8 July 2004

I probably haven't read all of the literature that has flowed from Charlie's prolific keyboard, so forgive me if this is well established background.

Given the rather numinous nebulosity and nebulous numinosity of Intelligent Design Design Theory, without nailing down some basics, one never knows exactly what one is arguing with.

I am pretty sure, for instance, that I am genetically descended from my parents, then grandparents, etc. and confidently extrapolate this process back into prehistory. Further, I find compelling the evidence that humans share a relatively recent ancestor with chimps, an older (but still recent relative to geological time) ancestor with the other primates, etc., and confidently extrapolate this process back to at least Cambrian times. Further, I can think of no compelling reason to look further than the basic explanation of "descent with modification" (as that process is understood by modern molecular genetics) to at least broadly understand these phenomena.

Does Charlie take issue with any of this so far?

I would love to know exactly what happened in preCambrian times, but details do get harder to come by looking back beyond that. We have to rely more on molecular evidence and less on durable specimens, but that's pretty much what one would expect, if one thinks that more complex forms evolved from less complex ones. Further, the molecular evidence is still startlingly compatible with the same processes of descent with modification stretching back way beyond the most ancient fossils.

Does Charlie take issue with any of this so far?

To really know the details of the origin of life would be the intellectual equivalent of, I don't know, landing a human on Alpha Centauri. I'm pretty sure it's not going to happen in my lifetime. Nonetheless, I don't see any reason why, in principle, we need to look further than the kinds of processes we've described, if we accept the hypothesis that the ultimate ancestral genome was a molecule capable of self-replication. (How that came to be, is of course another question. But I see no reason to require of it any more "complexity"/"information" than is necessary just for self-replication).

I think I've just sketched a view that is generally shared by most scientists. I'm pretty sure that somewhere along the line, Charlie would disagree. I think it might be helpful, if exchanges with a Paleyist are to be anything more than duels in the dark, to know exactly where he agrees and where he doesn't. But really, as Wes pointed out, there are no published reports showing the inadequacy of evolutionary processes. So it seems to me the onus is on the Paleyist to demonstrate his claim that "intelligent input" is either necessary or likely. So far as I know, Behe and Dembski are the only two who purport to do so, and their claims do not bear scrutiny.

Ian Menzies · 8 July 2004

Can you cite any particular reference from the literature that supports the notion that random processes have such power? After all, that is the crux of the matter. Dembski is arguing (and so am I) that intelligent input is required for evolution to proceed. You, apparently are arguing that it is not required, that it can be explained by random, accidental processes. Is there anything in the literature that is supportive of your position?

Well, Here's a page that includes a summary of Luria and Delbruck's 1943 paper that demonstrated that mutations which bestow resistance upon bacteria are random rather than arising in response to the anti-bacterial agent. I'm sure you'll just dismiss that as microevolution, but hopefully you at least acknowledge that random mutation which provides benefits can occur without regard to need. Now, in PZ Myers' post about MADS boxes (which I see you have read) he includes references to a paper that talks about plant evolution. In particular it discusses the probable evolution of the flower by co-option of existing parts, such as leaves, the evolution of more complex flowers from simpler flowers, and a phylogeny derived from homologies of the MADS box genes. So, we have regulatory genes which have been created through duplication and modification, complex structures which come about by modification and co-option of existing structures, and mutation which occurs randomly without regard to need. Seems perfectly compatible with blind variation and differential selection. Do you have any evidence for the intervention of an intelligent agent? All I have ever seen from ID is hand waving, appeals to ignorance and personal incredulity, and arguments based on philosophical objections.

Eddie Rios · 8 July 2004

Les Lane wrote: Charlie's conclusions are reasonable if one uses only propositional logic and considers only the macroscopic. Unfortunately, the microsopic level (DNA sequence) suggests entirely random processes. It seems to require more than average intelligence and insight to get beyond propositional logic and to see randomness.

The thing about propositional logic is that it does not necessarily have anything to do with an actual physical system. Even if DNA sequences occur via a random process in a population, they occur in an ecosystem which exerts selective pressures. Selective pressures are a non-ramdom thing.

I suspect Charlie Wagner is merely ignorant of how biology works.

charlie wagner · 8 July 2004

Les Lane wrote:

Unfortunately, the microsopic level (DNA sequence) suggests entirely random processes.

On the contrary, it suggests intelligent input. The sequence of DNA bases is not random, anymore than the bits in a computer program are random. They code for specific proteins that are used in specific structures and processes and they have specific functions. If the DNA sequences in the genome were random, no living organisms would ever emerge.

Mike Klymkowsky · 8 July 2004

I am sorry to say that the problem with debating ID creationists is that they have really nothing of value for a working biologist; ID theology is a scientific dead-end.

Their position is based on two unambiguous beliefs. First, that biological systems are too complex to arise by physical processes, chance and selection (an idea which they accept blindly and do not attempt to demonstrate through their own direct experiments). I am reminded of many previous assumptions, e.g., that organic molecules could not be synthesized outside a living cell, that were subsequently proven false (Wohler's synthesis of urea and the Miller-Urey experiment). Second, that an intelligent designer exists and manipulates the physical world (for which they offer no independent scientific evidence and propose no mechanism by which such interventions might occur, or could be detected). Since evolution demonstrably occurs (all the time), it should be possible to measure these periodic interventions, or find clear evidence for them.

I think what draws many, and certainly myself, to science is that it rarely wastes time in futile debate; in fact debate is a sign of uncertainty - the answer emerges not from discussion but through experiments and analysis. Once a question is resolved, we move on to the next question. While some questions, previously thought answered, have to be reconsidered in the light of new data, the end result is a progressive expansion of understanding.

Evolution theory is, in its board strokes, one such resolved question, and it leads to many fruitful new questions and ideas - the sign that a scientific process is taking place. ID is, as are all theological ideas, a dead-end -- the only reason that people propose it is that either, their religious beliefs demand it, they do not understand biology, or they have lost their faith in the explanatory power of the scientific process.

Les Lane · 8 July 2004

Pardon my insufficient concreteness. I'm referring here to DNA sequence "change" (mutation). DNA sequence "change" is what one observes in comparing DNA sequences (among related organisms). Familiarity with DNA replication, recombination, mutation and "neutral evolution" are called for here.

Tracy Hall · 8 July 2004

The real issue is that, as creationists, Charlie and his ilk insist that a single random event create all molecular structures as they are now - substituting a single "random" event for their single "creation" event. It presupposes a recent creation.

Molecular evolution (spoken as a mere dilletante) is a series of "random" events, biased by selective "pressures". The "randomness" is the undirected mutations; evolution is the "selection" from those undirected mutations by survival of whichever mutation "happens" to convey a survival and/or reproductive advantage.

Perhaps a poker analogy? Those players left at the table at the end of the night are those who could take advantage of the random deal of the cards. The deal is random; the play is not.

Charlie simply wants an easy choice, not a thought process; he wants his diety or the "random" diety, not a complex & messy process without a prescribed end.

Tracy Hall · 8 July 2004

The real issue is that, as creationists, Charlie and his ilk insist that a single random event create all molecular structures as they are now - substituting a single "random" event for their single "creation" event. It presupposes a recent creation.

Molecular evolution (spoken as a mere dilletante) is a series of "random" events, biased by selective "pressures". The "randomness" is the undirected mutations; evolution is the "selection" from those undirected mutations by survival of whichever mutation "happens" to convey a survival and/or reproductive advantage.

Perhaps a poker analogy? Those players left at the table at the end of the night are those who could take advantage of the random deal of the cards. The deal is random; the play is not.

Charlie simply wants an easy choice, not a thought process; he wants his diety or the "random" diety, not a complex & messy process without a prescribed end.

Chip Poirot · 8 July 2004

Since the subject of "research program" has been broached here, I'd be curious to get some perspective on the requirements for a "research program" from list participants.

Most, if not all, participants may recognize the term as Lakatos' which contrasts slightly with Kuhn's paradigm.

Research programs are complex-embodying accepted theories and even metaphysical assumptions. As such, they are not directly testable and never really "refuted".

The sign of advancing research program is its ability to generate valid, testable hypotheses and explain existing known "facts" as well as account for new ones.

Lakatos argues that this research takes place in the protective belt. Hypotheses generated in the protective belt are "testable".

My view is that in order to have testability, you must have falsifiability.

On the whole, it seems to me that ID **could** generate testable propositions, but thus far, it has done so to an extremely limited extent, and most of these propositions can be shown to be extremely weak, if not explicitly "falsified" at least at the theoretical level.

As an example, the argument that flagellum cannot evolve can be easily refuted-and has been refuted and thus I will not repeat the argument here. I suspect most list participants are familiar with the argumen and could do a better job than i can in stating it.

What do others think? Is there a possibility of an ID "research program"? What would it have to do?

Finally, what do others think-is falsifiability of propositions in the protective belt essential, possible or even desirable?

Isaiah · 8 July 2004

Ian to Charlie: I'm sure you'll just dismiss that as microevolution...

I don't know. Creationists used to dismiss that kind of evidence as just "microevolution". But aren't Dembski and Behe now making the claim that Darwinian processes can't create effective proteins? That would seem to rule out the possiblity of bacterial resistance occuring naturally. So now even the things they call "microevolution" seem to provide evidence against ID claims.

It seems to me that the only way the creationists can make these arguments hold together is either to make an artifical distinction between "creating a new protein" (which can't happen in their view) and "tweaking an old protein for improved function", or they will have to claim that everytime a bacteria/insect etc. gains a resistance gene the designer is at work behind it.

Adam Marczyk · 8 July 2004

This doesn't seem to be the first time Dembski has made a "just wait five years"-type statement. In 1998, he claimed that intelligent design would be worthy of funding from the National Science Foundation within five years:

http://www.talkorigins.org/origins/postmonth/mar02.html#hon2

I think we are now in a fairly definitive position to evaluate the accuracy of that prediction. It seems that the "imminent collapse of Darwinism" is a mirage, always retreating further and further over the horizon as the poor beleaguered IDers pursue it...

Pim van Meurs · 8 July 2004

On the contrary, it suggests intelligent input. The sequence of DNA bases is not random, anymore than the bits in a computer program are random. They code for specific proteins that are used in specific structures and processes and they have specific functions. If the DNA sequences in the genome were random, no living organisms would ever emerge

— Charlie
Of course the sequence of DNA bases is not random but that is not surprisingly given the selective forces. In other words, the non-randomness of DNA shows how information can be 'inserted' from the environment into the genome. But DNA bases do mutate and their effect is 'random' with respect to their immediate effect in a particular environment. Examples of how simple processes can increase the information in the genome, how such processes can lead to IC systems can be found in many places. Tom Schneider, Adami, Lenski all have shown how these simple processes can explain the information in the genome. Combine this with the fact that the genome is scale free and it can be shown how simple processes of gene duplication and divergence can explain the observed data. So while intuitively one may reject the notion that such simple processes can be effective, actual experiments show that the various claims by ID proponents are plainly fallacious and contradicted by fact. Examples include "No Free Lunch" theorems shows that evolutionary processes cannot explain the information in the genome, IC systems cannot be explained by Darwinian processes, law of conservation of information shows that natural processes cannot explain information, and so on. ID's arguments are not only purely eliminative and thus an appeal to ignorance but in addition they have not been shown to be in any manner relevant to scientific inquiry or knowledge and hopelessly flawed at the theoretical foundation. Contrary to Dembksi's hopes, molecular Darwinism is alive and well. And I guess deep down he knows, hence the reference to the 'Taliban'.

Harrison Bolter · 8 July 2004

Mr. Wagner wrote:

"If the DNA sequences in the genome were random, no living organisms would ever emerge."

Why not? What would prevent them (living organisms) from emerging over time?

Les Lane · 8 July 2004

A question. Would Dembski retract his statement if he understood mechanisms of DNA sequence change? Both Dembski and Charlie like DNA sequence statics, but seem oblivious to dynamics.

Russell · 8 July 2004

It's astounding, given ID's solid roots in religious fundamentalism, that Dembski has the cajones to bring up the Taliban.

RBH · 8 July 2004

(Adapted from my posting on ARN)

There are a number of eminent something-or-other-biologists in the table of contents of the special issue of Touchstone:

Phillip Johnson, Professor Emeritus of Biologico-Legal Studies
Edward Sisson, Assistant Professor of Biologico-Legal Studies
Richard Weikart, Associate Professor of Modern-European-Historico-Biology
Jonathan Witt, Assistant Professor of Fellow-of-DI-Biology
Graeme Hunter, Professor of Philosophico-Biology
Jay Richards, Vice President for Politico-Biology
Carson Holloway, Assistant Professor of Politico-Biology
David Mills, Editor of The Journal of Religico-Biology
Anthony Esolen, Professor of Poetico-Biology and author of Did Dante Write Darwin's OoS, or Was It Really Marlowe?
Paul Nelson, Visiting Assistant Professor of Philosophico-Ontogenetic-Depth-Biology; someday-to-be-author of the forthcoming-in-perpetuity On Common Descent

and, of course, the irrepressible

William A. Dembski, Research Associate Professor of Mathematico-Philosophico-Theologico-Biology and co-owner, Brazos Barbecue.

A representative selection of distinguished hyphenates, every one of them educated to the gills (or should that be branchial arches?) in something that is not biology.

RBH

With due deference and apologies to the University of Ediacara.

Reed A. Cartwright · 8 July 2004

RBH,

I find it funny how Krauze cherry-picks evolution supporters, whereas you looked at everyone in that issue.

Jason · 8 July 2004

Charlie W. states

And all of these reports support the notion that random processes and accidental mutations are incapable of generating complex, highly organized structures, processes and adaptations in which multiple processes and multiple structures support multiple functions and are integrated into the system in such a way that the structures and processes not only support their own functions, they also support the functions of other structures and processes and the overall function of the system.

"All" of them? Really? Charlie, have you personally read every single journal article that deals with molecular evolution? If so, how did you miss this? Molecular Evolution of a microRNA Cluster Tanzer A, Stadler PF.

Many of the known microRNAs are encoded in polycistronic transcripts. Here, we reconstruct the evolutionary history of the mir17 microRNA clusters which consist of miR-17, miR-18, miR-19a, miR-19b, miR-20, miR-25, miR-92, miR-93, miR-106a, and miR-106b. The history of this cluster is governed by an initial phase of local (tandem) duplications, a series of duplications of entire clusters and subsequent loss of individual microRNAs from the resulting paralogous clusters. The complex history of the mir17 microRNA family appears to be closely linked to the early evolution of the vertebrate lineage.

I would suggest that in the future, you drop the "all" from your assertion.

Russell · 8 July 2004

Jason: "I would suggest that in the future, you drop the "all" from your assertion."

Indeed. Which of the following would be a better choice?

(1)...... most
(2)...... some
(3)...... none

Andy Groves · 8 July 2004

Adam wrote:

This doesn't seem to be the first time Dembski has made a "just wait five years"-type statement. In 1998, he claimed that intelligent design would be worthy of funding from the National Science Foundation within five years

Well, I'm sure Dembski would agree that ID is worthy of NSF funding now. Nothing should be inferred from the inconvenient fact that ID is not currently funded by the NSF. (Nothing other than it represents further vicious censorship of creative spirits by a self-appointed elite of materialists. All we need to do is replace the journal editors and reviewers with more open-minded folks, and ID will have made it. And the people did rejoice, and did feast upon the fruitbats, and the orang-utans and the Intelligently Designed Barbecue™..........)

charlie wagner · 8 July 2004

Jason wrote:

"All" of them? Really? Charlie, have you personally read every single journal article that deals with molecular evolution?

Of course not...all of the reports that have come to my attention. Are you aware of anything in the literature that supports the position that the evolution of highly organized processes, structures and adaptations can occur through random, accidental occurences?

If so, how did you miss this?

It just so happens that I have read this report. I have a deep interest in microRNAs and follow this fairly closely. Keep in mind the question that we are discussing, whether or not evolutionary processes are the result of intelligent input or random, accidental occurences. I am not disputing that changes occur in processes, systems and structures over time, I am only questioning the mechanism of these changes. Nothing in this report even suggests that the evolutionary changes observed by the investigators are random or accidental. (Nor do they claim that they are intelligently guided). So while this is a very interesting report, it sheds no light on our problem.

steve · 8 July 2004

So while this is a very interesting report, it sheds no light on our problem.

That's correct. If you change 'our' to 'my'.

charlie wagner · 8 July 2004

Ian wrote:

a page that includes a summary of Luria and Delbruck's 1943 paper that demonstrated that mutations which bestow resistance upon bacteria are random rather than arising in response to the anti-bacterial agent.

This paper is 60 years old. A lot has happened in those intervening years. I posted a paper here a while back that demonstrated that much of this kind of resistance is the result of acquired elements such as plasmids and is not the result of random mutation.

Do you have any evidence for the intervention of an intelligent agent?

No.

Russell · 8 July 2004

Charlie: Can you cite any particular reference from the literature that supports the notion that random processes have such power?

Me: Can you cite any particular reference from the literature that supports the notion that they don't?

steve · 8 July 2004

Anyone who refers to the algorithm of evolution as 'random processes and accidental mutations' is just not worth arguing with.

Adam Marczyk · 8 July 2004

Well, I’m sure Dembski would agree that ID is worthy of NSF funding now. Nothing should be inferred from the inconvenient fact that ID is not currently funded by the NSF.

In that case, we could ask the advocates of ID inconvenient questions, like what theoretical advances have been made in ID since that statement was first made.

Isaiah · 9 July 2004

Charlie:

I posted a paper here a while back that demonstrated that much of this kind of resistance is the result of acquired elements such as plasmids and is not the result of random mutation.

Charlie, when you say "this kind of resistance" which of the following do you mean: 1) Most gains of resistance in nature are due to sharing of acquired elements and not to mutation. 2) Most gains of resistance in bacterial "mutagenisis" protocols such as the one in the Luria and Delbruck paper are due only to sharing of acquired elements and not to mutation. Because if it's #1, then that would be totally irrelevant to the discussion, and if it's #2, I'd really really like to see that reference if you don't mind providing it again.

Les Lane · 9 July 2004

Understanding the dynamics of DNA change is a key to understanding evolution. Understanding only DNA structure can mislead. If we didn't understand how rocks were formed, then intelligent design would be the obvious explanation for their existence. One has only to look at the early history of geology to confirm this.

charlie wagner · 9 July 2004

Isaiah wrote:

Charlie, when you say "this kind of resistance" which of the following do you mean: 1) Most gains of resistance in nature are due to sharing of acquired elements and not to mutation. 2) Most gains of resistance in bacterial "mutagenisis" protocols such as the one in the Luria and Delbruck paper are due only to sharing of acquired elements and not to mutation. Because if it's #1, then that would be totally irrelevant to the discussion, and if it's #2, I'd really really like to see that reference if you don't mind providing it again.

It makes no sense to discuss acquired elements with respect to the Luria-Delbruck experiments because mobile elements were not known at that time. (Well, Barbara knew about them, but Max and Sal scorned her opinions and mocked her, for which I hold them in everlasting contempt) Here are the references. Make of them what you will... Science, Vol 299, Issue 5615, 2071-2074 , 28 March 2003 Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis ABSTRACT: The complete genome sequence of Enterococcus faecalis V583, a vancomycin-resistant clinical isolate, revealed that more than a quarter of the genome consists of probable mobile or foreign DNA. One of the predicted mobile elements is a previously unknown vanB vancomycin-resistance conjugative transposon. Three plasmids were identified, including two pheromone-sensing conjugative plasmids, one encoding a previously undescribed pheromone inhibitor. The apparent propensity for the incorporation of mobile elements probably contributed to the rapid acquisition and dissemination of drug resistance in the enterococci. Also of interest: Science, Vol 303, Issue 5664, 1626-1632 , 12 March 2004 Mobile Elements: Drivers of Genome Evolution ABSTRACT: Mobile elements within genomes have driven genome evolution in diverse ways. Particularly in plants and mammals, retrotransposons have accumulated to constitute a large fraction of the genome and have shaped both genes and the entire genome. Although the host can often control their numbers, massive expansions of retrotransposons have been tolerated during evolution. Now mobile elements are becoming useful tools for learning more about genome evolution and gene function.

Andy Groves · 9 July 2004

In that case, we could ask the advocates of ID inconvenient questions, like what theoretical advances have been made in ID since that statement was first made.

To paraphrase Forrest and Gross, this will all be explained in Dembski's next book. Just you wait.

Jason · 9 July 2004

Charlie Wagner asks,

Are you aware of anything in the literature that supports the position that the evolution of highly organized processes, structures and adaptations can occur through random, accidental occurences?

Of course. I just gave you one example. Naturally, you try and fend off this example by arguing...

I am not disputing that changes occur in processes, systems and structures over time, I am only questioning the mechanism of these changes. Nothing in this report even suggests that the evolutionary changes observed by the investigators are random or accidental. (Nor do they claim that they are intelligently guided).

Ah I see. The ID you are proposing works in almost the same manner as evolutionary processes. In this case, we both agree that the mir17 cluster came about via a series of duplications and deletions, only you are arguing that such mutational events were "guided" or even directly carried out by some un-evidenced intelligent agent. Given that we have observed duplication events in the lab and been able to explain their occurence without need to invoke some sort of intelligent agent, I'm trying to figure out why you feel we suddenly need to posit some "designer" to explain the mir17 example. Are you suggesting that only this intelligent agent can cause duplications?

Jason · 9 July 2004

Russell asks,

Indeed. Which of the following would be a better choice? (1) . . . . . . most (2) . . . . . . some (3) . . . . . . none

Well, until Charlie presents a paper wherein the authors state something like, "Here we describe (insert complex structure and/or process) and explain why they could not have come about by random undirected events", I think the only honest choice would be #3.

Russell · 9 July 2004

As a microbiologist, I'm totally at a loss to understand why Charlie thinks mobile elements bolster his case.

It would be helpful if he would answer the questions I posed earlier.

steve · 9 July 2004

There are more things in cells and the earth, than are dreamt of in Charlie's philosophy.

Russell · 9 July 2004

Dembski: In the next five years, molecular Darwinism --- the idea that Darwinian processes can produce complex molecular structures at the subcellular level --- will be dead

And they say ID makes no predictions! Some website somewhere should have one of those "count-down" clocks: maximum # years/months/days before "molecular Darwinism" is predicted to be dead. I'll be generous and give it till January 1, 2010. Here's a prediction I'll venture: by 1/1/2010 Dembski et al will have declared the demise of molecular Darwinism; it just won't be apparent to anyone else. But they've got to be able to point to some concrete sense in which it is "deader" then than it is now, or our countdown clock flashes a huge banner: >>>>>>>>>>>>>>>>>>>>"GAME OVER"

Russell · 9 July 2004

(I swear I previewed that and the last line came out:

}}}}}}}}}}}}}} GAME OVER {{{{{{{{{{{{{{{{

except with >'s and ("less than's"). There seems to be something about the first "less than" sign that causes the rest of the message to disappear. Oh well, you got the idea)

Anyway, my fantasy countdown page might also keep a tally of papers published on molecular evolution per month, so we have some sense of its dwindling to zero by 1/1/2010

charlie wagner · 9 July 2004

Jason wrote:

In this case, we both agree that the mir17 cluster came about via a series of duplications and deletions, only you are arguing that such mutational events were "guided" or even directly carried out by some un-evidenced intelligent agent.

I agree to no such thing. Of course, gene duplication occurs, but I question its significance as an evolutionary mechanism. After all, the duplicated sequences would be exactly the same as the original so you must explain the next step, how they became "new". The authors state:

The microRNAs of the mir17 clusters arose through a complex history of duplication and loss of individual members as well as duplications of entire clusters.

I think this conclusion is highly speculative and not supported by any empirical data. It is based on the sequence analysis and distances of the various components which are used to construct phylogenetic trees using computer programs. I don't think there is any basis for assuming that these kinds of comparisons have any evolutionary significance. So the conclusions are based on unproven assumptions and therefore I consider them to be of little value. If it could be established that there was an evolutionary relationship such as they propose, it still would not help us to know whether the evolution of these sequences was random or intelligently guided.

Dave S · 9 July 2004

Of course, gene duplication occurs, but I question its significance as an evolutionary mechanism. After all, the duplicated sequences would be exactly the same as the original so you must explain the next step, how they became "new".

— Charlie
Man. If only there was a way for this new gene to change one or some of it's base pairs, then problem solved. Too bad that doesn't exist, cause then the genes would be in evolution hog city.

I think this conclusion is highly speculative and not supported by any empirical data. It is based on the sequence analysis and distances of the various components which are used to construct phylogenetic trees using computer programs. I don't think there is any basis for assuming that these kinds of comparisons have any evolutionary significance. So the conclusions are based on unproven assumptions and therefore I consider them to be of little value.

And your superior explanation of the data would be ...

If it could be established that there was an evolutionary relationship such as they propose, it still would not help us to know whether the evolution of these sequences was random or intelligently guided.

Aren't there three doors here? What happened to non-random but nevertheless not intellegently guided?

Isaiah · 9 July 2004

Charlie (comment #4791): It makes no sense to discuss acquired elements with respect to the Luria-Delbruck experiments because mobile elements were not known at that time.

I guess by this logic, it makes no sense to talk about early hominid evolution, since early hominids didn't know about evolution.

Seriously, Charlie, sorry for the breach of courtesy here, but I think you are totally missing the point here, unless you are deliberately avoiding it.

Luria and Delbruck (1943) was brought up as an example of random mutations leading to gain of function. In response, you mention mobile genetic elements. But what do mobile genetic elements have to do with the Luria and Delbrok paper? You cite no evidence and make no argument to suggest that the spontaneous gain of resistance seen in Luria and Delbruck could occur without mutation. Therefore your comments about mobile genetic elements are irrelevant to the discussion. That's what I was trying to get across.

Great White Wonder · 9 July 2004

Chaz has a New Pony:

the duplicated sequences would be exactly the same as the original.

Charlie, are you asserting here that DNA replication is 100% accurate in every instance? I surely hope not. That is quite wrong. Replication and gene duplication can lead to changes (known as mutations) in the replicated and duplicated sequences. These changes may have no effect, subtle effects, or profound effects on the structure and function of the duplicated or replicated genes, depending on the type of mutation and its location in the structural gene. Now that you have been made aware of the fact that DNA replication (including gene duplication events) may lead to changes (known as mutations) in the replicated and duplicated sequences, you surely realize that your previous arguments are bogus. You're welcome to start over. Good luck!

Jason · 9 July 2004

Charlie states,

Of course, gene duplication occurs, but I question its significance as an evolutionary mechanism. After all, the duplicated sequences would be exactly the same as the original so you must explain the next step, how they became "new".

So you claim to be very familiar with the published literature, yet you are totally unaware of duplication and divergence? Are you suggesting that the duplicate is unable to undergo further mutation? Charlie asserts,

I think this conclusion is highly speculative and not supported by any empirical data.

The authors' proposed pathway explains the cluster quite well and does so by relying on mechanisms that have been observed in the lab. Your version of ID on the other hand, relies on unknown mechanisms carried out by an unevidenced "designer". You'll understand if I side with the evolutionary explanation. Finally, Charlie states,

If it could be established that there was an evolutionary relationship such as they propose, it still would not help us to know whether the evolution of these sequences was random or intelligently guided.

Ah, preemptively moving the goalposts? At least we can get an idea of what the next morph of ID will be. "Yeah sure, various mutations led to the development of X, but God/aliens/time-traveling scientists caused those specific mutations!"

Les Lane · 9 July 2004

Charlie-

We're dealing here with what Alfred North Whitehead calls "misplaced concreteness".

"We typically accept a high level of abstraction in what we believe and demand a high level of concreteness when we disbelieve."

We're operating at some level of abstraction. You seem to want documentation of sequence changes nucleotide by nucleotide. We assume familiarity with common methods of sequence change. If you're serious about conversing with us, you'd do well to brush up and deal with us at a slightly higher level of abstraction.

charlie wagner · 9 July 2004

GWW wrote:

You're welcome to start over. Good luck!

As my students used to say to me: "Mr. Wagner, you're a pissa...!"

Jack Krebs · 9 July 2004

Charlie writes,

If it could be established that there was an evolutionary relationship such as they propose, it still would not help us to know whether the evolution of these sequences was random or intelligently guided.

We can never know if the "random" events of the world are actually intelligently guided but just look random. If I roll a die, how could one ever tell that God didn't subtley manipulate one bounce (at a level beyond our ability to measure) and with his omniscient understanding of the fractal nature of historical paths, cause the die to come up 6? We can't. Many theists believe that God has the ability to act in the world in ways that do not contravene natural processes and that are beyond our understanding. From such a perspective, all events which include random and contingent events (including evolution) are intelligently guided. But this guidance takes place in a manner undetectable by science, and therefore can not be included in science. (And of course, people with other metaphysical beliefs don't see things the same way, but they see the same science.)

charlie wagner · 9 July 2004

Les wrote:

We're dealing here with what Alfred North Whitehead calls "misplaced concreteness".

How interesting. Bertrand Russell was a student of Wallace and I was a student of Russell. Not directly, although I met Russell on several occasions and worked with him in the SANE group when I was in college. I was a student of his advocate, Paul Edwards, who is the editor of "Why I Am Not A Christian", a collection of Russell essays. One sublime moment that I recall was greeting Lord Russell with a friendly, "Hi! How are you today?" His reply to me? "In relation to what?" http://www.positiveatheism.org/hist/russell0.htm This "fallacy of concreteness" involves thinking that something is a concrete reality when in fact it is simply an opinion, belief, or concept about the way things are. And a false belief in something is a delusion - and delusions can be dangerous. So be careful not to become too abstract about these matters, because there is much danger of deluding oneself into thinking that these abstractions are reality. A good example of this are simulations that purport to "model" evolution. In the area of science, abstractions are good for generating hypotheses, but these hypotheses must always be tested to ensure that they correctly represent reality.

charlie wagner · 9 July 2004

Jack wrote:

We can never know if the "random" events of the world are actually intelligently guided but just look random. If I roll a die, how could one ever tell that God didn't subtley manipulate one bounce (at a level beyond our ability to measure) and with his omniscient understanding of the fractal nature of historical paths, cause the die to come up 6? We can't.

True enough. However, since there is no empirical evidence that such a supernatural entity with such powers exists, it makes no sense to consider this possibility in our everyday affairs. We have to make our choices and think our thoughts within the context of what we know to be true, not what we imagine might be true. We know there is such a thing as intelligence and we can define it and to some degree, measure it. So it's reasonable to include it in our thinking process. Likewise, we know that certain events are random, and we can define random and we can model randomness. We have to be careful here because we might see intelligent guidance where there really is none. In the dice example, one might suspect that since when you roll the dice, you get "boxcars" once every 36 tosses. This might lead one to suspect that design is involved, but a closer examination shows that there is no such design in the tossing of a dice. The fact that a certain combination comes up once every 36 times is nothing more than a statistical average that flows from random chance. On the other hand, there are cases where it can be clearly determined that random chance is not at work. This would occur in any system, such as a machine, in which multiple structures exist and multiple processes exist and each of these structures and processes have a function. In addition, if these varied structures and processes are integrated in such a way that their functions support each other and also support the overall function of the system, it becomes clear that such an entity cannot, by any known mechanism, have arisen by random chance. The reason for this is because in the design and assembly of the system an additional factor was required, insight. Living organisms are such systems and they can clearly and definitively be determined to be beyond the realm of random chance.

Great White Wonder · 9 July 2004

So be careful not to become too abstract about these matters, because there is much danger of deluding oneself into thinking that these abstractions are reality.

My head just exploded.

charlie wagner · 9 July 2004

GWW wrote:

My head just exploded.

Hang in there, laddie, there's more to come...

Russell · 9 July 2004

Charlie: I was a student of Russell

I categorically deny it.

Though I would be honored if he would address my comments #4733 and #4763.

G3 · 9 July 2004

On the other hand, there are cases where it can be clearly determined that random chance is not at work.

— Charlie Wagner
As opposed to that non-random chance ;-) Good point Charlie, as every biologist will tell you, Evolution only consists of random events. This is due to all biological niches being infinite in size, so that there is never any competition for resources. Also, since living things do not reproduce, there is no selection for any of these random mutations that confer a reproductive advantage.

Pim van Meurs · 9 July 2004

Charlie: A good example of this are simulations that purport to "model" evolution. In the area of science, abstractions are good for generating hypotheses, but these hypotheses must always be tested to ensure that they correctly represent reality.

Hence why Dembski's 'models' for evolution have to be rejected? Hence why ID's approaches have to be rejected?

Well said

Les Lane · 9 July 2004

Charlie-

When it comes to concreteness we're not necessarily talking fallacies. We're talking about communication failure due to operating in different spheres. Evolution involves many abstractions. To make useful discussion at the concrete level I'd suggest sticking to specific questions.

Bob Maurus · 10 July 2004

Ah, Charlie,

It comes full circle back to Horatio's Hypothesis: "Every CSI exhibiting object for which a causal history is known, is known to be the result of human agency. We observe in the Natural World living entities which exhibit CSI. Having empirical evidence of only one Designer, it is reasonable to infer that those CSI exhibiting entities are the result of human agency."

Pim van Meurs · 10 July 2004

Charlie still confuses random chance with evolutionary explanations it seems

On the other hand, there are cases where it can be clearly determined that random chance is not at work. This would occur in any system, such as a machine, in which multiple structures exist and multiple processes exist and each of these structures and processes have a function.

What about the Circadian clock for instance Charlie? Function is an inevitable outcome of evolution as are multiple structures. Seems that design in nature is not as much the issue as is the nature of the designer? That's where ID totally fails since it is based on appeal to ignorance.

charlie wagner · 10 July 2004

Russell wrote:

Though I would be honored if he would address my comments #4733 and #4763.

Unfortunately, there's only one of me and a lot of you guys. I try to answer everybody when possible. If you go to my website, you'll find a lot of information and you can also go to talk.origins and Google on my name. I am always ready to answer specific questions if you have any. The literature doesn't adress directly the issue of random processes or intelligent input. These are interpretations that investigators put on the data. My belief is that as more is learned about the organization, structure and functions of living systems the more obvious it becomes that such systems could not have arisen without insight.

Russell · 10 July 2004

Charlie: Unfortunately, there's only one of me and a lot of you guys. I try to answer everybody when possible. Hmmm. Interesting perspective. One "Paleyist" vs. a lot of "Darwinists"? One "iconoclast" vs. a lot of "orthodox"? One "crank" vs. a lot of "mainstream"? Anyway, I don't know your web site, and unless it's a whole lot better organized than the comments posted here, I don't want to spend more than a few minutes on it. I just want to know, basically, two things. 1. Where, exactly, do you part company with mainstream biology? E.g., do you accept that humans and chimps are descended from a common ancestor? humans and fish? humans and palm trees? 2. Can you show us even one example to back up this assertion:

And all of these reports [of research into evolutionary phenomena] support the notion that random processes and accidental mutations are incapable of generating complex, highly organized structures, processes and adaptations in which multiple processes and multiple structures support multiple functions and are integrated into the system in such a way that the structures and processes not only support their own functions, they also support the functions of other structures and processes and the overall function of the system.

Jack Krebs · 10 July 2004

I have similar questions about the qoute Russell posted of Charlie's - what reports establish Charlie's claim as opposed to all the standard philosophical creationist arguments that do not actually point to any empirical evidence?

Richard Wein · 12 July 2004

Dembski: In the next five years, molecular Darwinism --- the idea that Darwinian processes can produce complex molecular structures at the subcellular level --- will be dead.

Anyone want to take a bet that, in five years time, Dembski will still be saying "In the next five years..."?

Les Lane · 12 July 2004

A quantitative study of molecular Darwinism. Comments welcomed.

Bob Maurus · 12 July 2004

Les,

Did you also do a search for "molecular darwinISM that got no matches?

Russell · 12 July 2004

I love it. Now all we need is the countdown clock!

(Also - might want to fix this typo:
"predicition")

Les Lane · 13 July 2004

Bob-

I searched for molecular darwin*

The wildcard searches all suffixes

Bob Maurus · 13 July 2004

Thanks Les, figured you knew what you were doing, but wasn't sure how the searches work.

Nick (Matzke) · 10 December 2004

Pertinent to this, Sonleitner says in a Pandas update:

Microbiologists have estimated that there are 5 x 1024 bacteria living on earth in the ocean, in the soil, beneath the surface, in the air, and inside animals. Soil and subsurface habitats account for 94%; the insides of animals account for only a fraction of 1 percent. In the oceans, any given bacterial gene is estimated to undergo an average of 4 mutations every 20 minutes (Anonymous 1998). [...] [Anonymous]. Whole lotta bugs. Discover 1998 Dec; 19 (12): 28.

I have seen something similar in An Official Journal like PNAS. Ah yes:

Genes that are widely distributed in prokaryotes have a tremendous opportunity for mutational change, and the evolution of conserved genes must be otherwise greatly constrained. Assuming a prokaryotic mutation rate of 4x10^-7 mutations per gene per DNA replication (86, 87), four simultaneous mutations in every gene shared by the populations of marine heterotrophs (in the upper 200 m), marine autotrophs, soil prokaryotes, or prokaryotes in domestic animals would be expected to occur once every 0.4, 0.5, 3.4, or 170 hr, respectively. Similarly, five simultaneous mutations in every gene shared by all four populations would be expected to occur every 60 yr. The capacity for a large number of simultaneous mutations distinguishes prokaryotic from eukaryotic evolution and should be explicitly considered in methods of phylogenetic analyses. [William B. Whitman, David C. Coleman, and William J. Wiebe (1998). Prokaryotes: The unseen majority. PNAS. Vol. 95, Issue 12, 6578-6583.]

Nick (Matzke) · 10 December 2004

[wrong thread, ignore previous post]

Rilke's Granddaughter · 10 December 2004

[wrong thread, ignore previous post]

Curiosity compels me to ask: what was the right thread?

RBH · 10 December 2004

RGD asked

Curiosity compels me to ask: what was the right thread?

This one. RBH