The issue of Nature Reviews Genetics from which I pulled the Homeobox genesis article actually contains a whole series of articles focusing on evolution of the body plan. Here's a brief taste of the good stuff found in the journal:
Garcia-Fernàndez J (2005) The genesis and evolution of homeobox gene clusters. Nature Reviews Genetics 6:881-892.
The crucial function of homeobox genes in patterning the body has been appreciated for decades. This article pulls together existing data to explain how the current clustered organization of Hox genes, and that of the related ParaHox and NK clusters, came about, the forces that preserve gene clustering and the contribution of Hox, ParaHox and NK genes to the major evolutionary transitions in animal body plan.
Pearson JC, Lemons D, McGinnis W (2005) Modulating Hox gene functions during animal body patterning. Nature Reviews Genetics 6:893-904.
The function of Hox proteins in axial patterning and morphological evolution ultimately depends on the effects of these proteins on downstream targets. This article reviews four important lines of research into Hox function - including work to identify the nature of Hox targets and define the structure of target enhancers, and the recent realization that Hox gene expression might be modulated by conserved microRNAs.
Peel AD, Chipman AD, Akam M (2005) Arthropod segmentation: beyond the Drosophila paradigm. Nature Reviews Genetics 6:905-916.
Genetic studies of Drosophila melanogaster have laid the foundations of our understanding of axial development. But just how universal is this fly model? The growing number of experimental methods that have become available for other arthropods is revealing a surprising diversity of pattering mechanisms, and allows us to formulate a model of how segmentation mechanisms might have evolved.
Martindale MQ (2005) The evolution of metazoan axial properties. Nature Reviews Genetics 6:917-927.
Multicellular animals come in many shapes and forms but they owe their body organization to the emergence of three design features - the anterior-posterior and dorso-ventral axes, and the three germ layers. Morphological and, more recently, molecular analyses on four basal metazoan taxa have begun to reveal how such features emerged and evolved, although a consensus model will depend on a stronger phylogenetic framework and a broader sampling of informative taxa.
Keep that all in mind next time a creationist tries to tell you that evolution is superfluous, or that Intelligent Design has a research plan.
64 Comments
Steviepinhead · 16 December 2005
Cool, PZ. It would almost be worth the $30 a pop to download some of these, particularly the arthropod segmentation and basal metazoan ones.
Sigh, I guess I'll just have to wait for [insert your favorite seasonal excuse for benevolence].
Thanks for at least unwrapping the pretty Hos clusters package for us!
minimalist · 17 December 2005
Oh, but PZ, the Discovery Institute does have a research plan, according to Jonathan Wells!
I am ashamed to say that this past Wednesday, he presented a poster at the latest meeting of my society (the ASCB), and it's a doozy of crank science. Pretty much a word salad of buzzwords and nonsense, trying to link the DI's latest hobbyhorse -- "centrioles = turbines! also the cytoskeleton = highways, and like, the Golgi is a dumptruck or some damn thing, VROOM VROOM REEOOOOWWWW" -- with cancer.
I am doubly ashamed to say that I lacked a camera, though a friend got some high-quality pictures and I am pressing him to get them posted so the content can be transcribed online for posterity. In the meantime you can at least view the abstract for yourself and judge its merits. The poster, needless to say, said little more than that, only using more words.
At any rate, Wells assured my friend that an experiment to test this hypothesis was, indeed, forthcoming, so I'm sure we can all look forward to that!
Of course, Wells' poster also claimed that it had put forward an "experimental strategy" (even though, as far as I can recall, no experimental detail was ever supplied, and his response to my friend was pretty much "we got it covered, awright?") and that this so-called "model" could somehow, in some mysterious, undetailed way, be used as a diagnostic for cancer (how, are you going to test whether someone's cells can propel a jet airplane or what?).
Exciting, cutting edge research is coming from the DI! Any day now! Any... day... I'm sure of it...
Norman Doering · 17 December 2005
Alan Fox · 17 December 2005
Norman
Remember this is Josh Bozeman posting. His inability to see the projection, inconsistency and irony in his own comments is breathtaking. It never ceases to amaze me that Dembski allows such drivel on his blogsite. However, as someone else pointed out recently, it all contributes to the undermining of Dembski as having any remaining credibility.
Alan Fox · 17 December 2005
Norman
I'll give it a go for you. What is the French word for "Fox"?
jim · 17 December 2005
Alan,
Try "Renard".
Alan Fox · 17 December 2005
Jim, follow Norman's link and scroll to comment #8. All should be revealed.
jim · 17 December 2005
Alan,
Kool!
k.e. · 17 December 2005
hehehehehe
Renard Tres Bien
Ecoutez voir
Tautology AND navel gazing AT THE SAME TIME.
That can lead to dangerous consequences
Like ID being sucked up its own fundament
'Rev Dr' Lenny Flank · 17 December 2005
mynym · 17 December 2005
Somewhere, a cock is crowing thrice before morning.
If you were not wound so tightly into the notion that Darwinism supports philosophic naturalism the you would see that natural vs. "unnatural" is not the main issue.
If a biotech company succeeded in designing a self-replicating automata, a sort of organism based on nanotechnology would you call that "natural" or "unnatural"? Whatever you might call it, it would still be designed...and we'd probably all be dead, depending on the rate of self-replication and what they made it run on. For all the typical Darwinian pretentions as per the "panda's thumb" argument about how they could design things "better" than the organisms we observe humans cannot even manage this ecosystem well, let along actually design organisms that would live "better" or fit into ecological systems well.
mynym · 17 December 2005
Exciting, cutting edge research is coming from the DI! Any day now! Any... day... I'm sure of it...
I suppose if Darwinian proto-Nazis hadn't wormed their way into a closer and closer alliance with the State and worked to censor any opposition as they typically do, then the DI would recieve millions in State funding to do the research that you demand... and supposedly desire.
k.e. · 17 December 2005
Somewhere A Parody projected
If
youI were not wound so tightly into the notion thatDarwinismCreationism supports philosophic naturalism the(sic)youI would see that natural vs. "unnatural" is not the main issue.If a biotech company succeeded in designing a self-replicating automata Bacteria?, [If a nano-tech company succeeded in designing a self-replicating automata] a sort of
organismmachine based on nanotechnology would you call that "natural" or "unnatural"?[Parody........ if you don't know the difference find a cat and ask it]
Whatever you might call it, it would still be designed...and we'd probably all be dead [yeah, yeah, yeah post modern nihilism], depending on the rate of self-replication and what they made it run on [NOT DI progoganda thats for sure].
For all the typical
DarwinianCreationist pretentions as per the"panda's thumb"DI argument about how they could designthingsGOD(s) "better" than the organisms I.E. humans we observe, humans[Conservatives] cannot even manage this ecosystem well, let along(sic) actuallydesignPROGRAM/PREACH TOorganismsmachines/robots/2 legged sheep/christian soldiers that would live "better" or fit into ecological systems well.John Marley · 17 December 2005
Do you notice that once their arguments are revealed as bad sleight of hand (er, mouth), the IDiots resort to cheap insults. Hey, If you can't win the argument, call your opponent a Nazi! That'll show 'em.
k.e. · 17 December 2005
Somewhere A Parody projected......the real DI agenda
I suppose if
DarwinianCreationist proto-Nazis hadn't wormed their way into a closer and closer alliance with the State and worked to censor any opposition as they typically do, then the DI would recieve millions in State funding to do the research that you demand... and supposedly desire.And just to remind everyone the Nazis justified everything they did in the name of GOD.
All the while claiming to be Christian with perfectly projected hatred for the truth.
Question for you mynym .... who said this ?
"
Christ's goal was clear and simple: "Love your neighbor as yourself." He gathered his followers behind that straightforward statement. Because this teaching was simple, crisp, clear, and understandable, enabling the broad masses to stand behind it, it in the end conquered the world."
Not sure ?
http://www.calvin.edu/academic/cas/gpa/goeb54.htm
Alan Fox · 17 December 2005
'Rev Dr' Lenny Flank · 17 December 2005
'Rev Dr' Lenny Flank · 17 December 2005
'Rev Dr' Lenny Flank · 17 December 2005
qetzal · 17 December 2005
Norman Doering · 17 December 2005
'Rev Dr' Lenny Flank · 17 December 2005
Alan Fox · 17 December 2005
Ben · 17 December 2005
It's offtopic, but is keiths on Dembski's blog a poster here? I'm curious as to how he seems to be shredding the arguments of Dembski's toadies but hasn't yet been banned.
Alan Fox · 17 December 2005
Me too, but let's not blow his cover.
Steve S · 17 December 2005
Lenny, you might be interested in the current "Mother Jones" issue. Big piece on Christian Reconstructionists. Those people are f*cking crazy.
'Rev Dr' Lenny Flank · 17 December 2005
'Rev Dr' Lenny Flank · 17 December 2005
Norman Doering · 17 December 2005
Alan Fox · 17 December 2005
Norman
Your links seem to suggest the possibility of terrestrial bacterial spores surviving embedded in nooks or crannies on spacecraft, and more controversially, in meteorites or similar space debris. I suppose it does increase the time and the available environmental diversity in which abiogenesis must have necessarily occurred. I'm with Robert Shapiro in thinking we haven't begun to scratch the surface of this mystery, but it is hugely intriguing.
PS did you see comment #63230?
Norman Doering · 17 December 2005
jean · 17 December 2005
Norman, do you know the concept of "exapation" ?
jean · 17 December 2005
Sorry, I meant "exaptation".
Norman Doering · 17 December 2005
Exaptation, or "preadaptation," adoption of a character that had one use in an ancestral form into a new, different use in a descendant form.
Do you know how unearthly and deadly the lunar environment is? Radiation, extreme temperatures, vacuum, ... and the microbes are a very small colony there for only three years. Not much time or starting material for evolution or even exaptation adaptions.
Alan Fox · 18 December 2005
Norman
Have you considered that outer space could be a preserving environment for a bacterial spore, akin to freeze-drying. Just enclose it in enough debris to protect it from radiation, and it might survive indefinitely. Just drop on suitable planet, add water and bingo. Still leaves you with the ultimate question, though, in some other time and place.
jean · 18 December 2005
Bacteria are simple organisms, adapted to various hostile environments on Earth, ranging from extreme cold to very high temperatures, the absence of light or oxygen... Thanks to the adaptations they developped on Earth (including sporulation), they may be able to survive in space, even if they never experienced such environment.
This is the definition of "exaptation".
Norman Doering · 18 December 2005
'Rev Dr' Lenny Flank · 18 December 2005
Norman Doering · 18 December 2005
Alan Fox · 18 December 2005
And from wherever or to wherever microbes may have travelled, we still eventually run up against the buffers of abiogenesis. We know it occurred because we are here, but how and why it happened is now and may always remain a philosophical question.
Norman Doering · 18 December 2005
Norman Doering · 18 December 2005
KiwiInOz · 18 December 2005
Perhaps the Right Wing Professor should have a word to Mr Buchanen - to disabuse him of the idea that evolution is a liberal plot, therefore without merit. RWP better watch out though, he might get portrayed as a 5th columnist.
'Rev Dr' Lenny Flank · 18 December 2005
Chris Booth · 18 December 2005
Just wanted to note other critters that, as a byproduct of the robustness that enables them to survive conditions of an extremity far beyond our capability, including drought and vacuum, could possibly qualify for Demon Ex-Terra Micro-Pandas in Outer Space:
Water bears!
http://www.astrobio.net/news/modules.php?op=modload&name=News&file=article&sid=261
and
http://www.museums.org.za/bio/tardigrades/
and, in one's own backyard:
http://www.microscopy-uk.org.uk/mag/indexmag.html?http://www.microscopy-uk.org.uk/mag/artmay99/dwbear.html
...wonderful, aren't they? But isn't the universe as it is so much richer than what small minds can imagine? Gas pillars of the Eagle Nebula, tardigrada; as Wallace Stevens said:
O thin men of Haddam,
Why do you imagine golden birds?
Tim Hague · 19 December 2005
Alan Fox · 19 December 2005
Tim
Meteor strike throws out debris into space; a lump is large enough not to get hot enough to incinerate resident bacterial spores; lump ends up drawn down to another planet, still big enough to avoid incineration of cargo, and ...bingo.
OK, I'm not even convincing myself. Never mind. (And too many enoughs!)
Alan Fox · 19 December 2005
Tim
Meteor strike throws out debris into space; a lump is large enough not to get hot enough to incinerate resident bacterial spores; lump ends up drawn down to another planet, still big enough to avoid incineration of cargo, and ...bingo.
OK, I'm not even convincing myself. Never mind. (And too many enoughs!)
Alan Fox · 19 December 2005
La vache!
Xcuse double post. I promise I refreshed to see if post had registered first time.
'Rev Dr' Lenny Flank · 19 December 2005
Tim Hague · 19 December 2005
Tim Hague · 19 December 2005
That should read... therefore no gravity problems...
Alan Fox · 19 December 2005
Aside to Norman
No more relaying questions by me on to Dembski's blog for you, my lad.
I've been rumbled.
Paul Flocken · 19 December 2005
Meteors from other planets.
http://www2.jpl.nasa.gov/snc/
The reverse is emminently possible. Blasting rock into space does not necessarily incinerate it and meteorites will have pristine material within them, after they have landed, if they are large enough. Heat due to re-entry isn't really from the meteor anyway.
http://www.space.com/scienceastronomy/top5_myths_020903-5.html
Sincerely,
Paul
Paul Flocken · 19 December 2005
Tim said
"It's not my theory, but assuming a planet buster meteor - one that quite literally smashes a planet into pieces - you wouldn't have a planet any more - just bits of one - therefore [no] gravity problems. I'm not sure however what the likelyhood is of anything at all surviving that!"
Not quite. Turning a planet into a bag of rocks won't eliminate the gravity those rocks have collectively. Quite a few of the smaller bodies of the solar system show evidence of having been turned into a bag of rocks and then having reassembled(due to gravity) into a whole again.
Sincerely,
Paul
Ben · 19 December 2005
Norman Doering · 19 December 2005
jim · 19 December 2005
I'd further point out that although we now think panspermia is possible, it still requires a lot of low probability events (LPEs) to occur.
Given the length of time available for it to occur (and the number of LPEs required for abiogenesis), it still is in the realm of possibility. However, panspermia requires its set of LPEs to occur in addition to those of the abiogenesis LPEs.
My conclusion is that its possible, but I'm disinclined to favor it unless I see some evidence that supports it (and no other explanation).
Alan Fox · 19 December 2005
Norman
Mars has some surface features that are difficult to explain other than by erosion by liquid water.
Norman Doering · 19 December 2005
sir_toejam · 19 December 2005
Alan Fox · 19 December 2005
I think Dembski has granted DaveScot some editorial responsibility, for example, see this post. Bill and his psychopathic sidekick make a lovely couple. I'm saving the screen-shots, you never know when someone might want a repeat performance of "Street theatre".
Alan Fox · 19 December 2005
Re Chris Booth's earlier post (sorry thought it was just a joke and didn't check links before). Thank goodness for the cube/square law!
Ben · 20 December 2005